Question of the Day – Thursday September 23, 2021
What is Pibloktoq? Pibloktoq, or “Artic Hysteria” is a “culture bound syndrome” of behavioral disturbance that has been proposed to have origins in environmental, nutritional, and psychological origins. The author of the cited refrence argues that cultural or social factors may be the true origin…
Question of the Day – Wednesday September 22, 2021
In a retrospective review of gabapentinoid related deaths in Australia from 2000-2020, what was the frequency of detection of opioids and sedative hypnotics? Drugs other than gabapentioids were detected in 99.8% of cases. Opioids were detected in 90.1%, and sedative hypnotics in 76.9%. Of note,…
AACT recommends against the routine use of ivermectin for treatment for COVID-19.
AACTion ITEM: The general public is using ivermectin as a treatment for COVID-19. RESPONSE: Ivermectin is a broad spectrum anti-parasitic agent that is FDA approved to treat the tissue microfilariae of Onchocerca volvulus and the intestinal stage of Strongyloides stercolis, but also used to treat…
Question of the Day – Tuesday September 21, 2021
Bloom of which species of dinoflagellate has recently been attributed to death from paralytic shelfish poisoning in Alaska? Alexandrium Catenella bloom resulted accumulation of saxitoxin in blue mussels and dogwinkle snails. Ingestion of these self harvested mollusks resulted in death of a patient in a…
Question of the Day – Monday September 20, 2021
What were the main findings of a 12 year retrospective study on pediatric ED visits for cannabis intoxication in Toronto from 2008-2019? “Children with cannabis-related ED visits in the peri-post legalization period experienced significantly higher rates of ICU admission compared to those who presented in…
NACCT Planning Committee Announces Virtual Meeting in October 2021
NACCT Main Congress October 16-18, 2021 The NACCT planning committee has made the difficult decision to move from a hybrid congress to an all-virtual format. The decision was difficult, but with speakers, moderators and poster presenters unable to travel due to the threat of COVID-19…
Question of the Day – Friday September 17, 2021
In 21 patients treated with repeated titrated doses of digoxin-Fab, what was the median total dose of digoxin-Fab? Chan BS et al. reported experience with titrating doses of digoxin antibodies in acute digoxin poisoned patients and in 21 patients, the median dose of digoxin-Fab was…
Question of the Day – Thursday September 16, 2021
What are the most commonly reported clinical effects after perampanel overdose? In a recent retrospective review of the National Poison Data System, drowsiness, agitation, ataxia and confusion were the most frequently reported clinical effects after perampanel overdose. Minhaj FS et al. Clinical effects and outcomes…
Question of the Day – Wednesday September 15, 2021
This antidote has recently been shown to generate thiocyanate by directly interacting with cyanide. Sodium tetrathionate. Chan A et al. Development of sodium tetrathionate as a cyanide and methanethiol antidote. Clin Tox Published online July 2021. https://doi.org/10.1080/15563650.2021.1953517
Question of the Day – Tuesday September 14, 2021
In 20 out of 266 patients who presented to the emergency department after an opioid overdose 19/20 (95%) tested positive for fentanyl. Most required no venipuncture and were ineligible for the study. Was there a correlation between naloxone dose equivalents and blood fentanyl concentrations? No….