Question of the Day – Thursday July 8, 2021
A recent study using a pyrolysis chamber to simulate the combustion of cannabidiol in e-cigarette devices, using reference grade cannabidiol, detected several other cannabinoids following pyrolysis. What were these? In this study, under either oxidant or inert conditions, cannabidiol, delta-9 THC, delta-8 THC and cannabichromene…
Question of the Day – Wednesday July 7, 2021
The alkaline Beam test was described in the early 20th century as a method to detect what substance? The alkaline Beam test was used to identify cannabis plant material. A specimen of the suspected plant material was mixed with an organic solvent, the extract dried…
Question of the Day – Tuesday July 6, 2021
What is the recommended observation time to monitor patients after an ACE inhibitor overdose if they are asymptomatic? A retrospective review of 33 patients who presented after an ACE inhibitor overdose found that maximal blood pressure lowering occurred around 5 hours after ingestion irrespective of…
Question of the Day – Friday July 2, 2021
What antipsychotic has been associated with fatal cases of diabetic ketoacidosis at therapeutic doses? Olanzapine. Avella et al. reported three fatal cases of diabetic ketoacidosis in patients with therapeutic olanzapine levels, despite no prior history of diabetes. Avella, Joseph, Wetli, Charles V, Wilson, James C,…
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Question of the Day – Thursday July 1, 2021
What structurally similar GABA-B agonist has been shown to successfully treat patients with dependence on the dietary supplement phenibut (β-Phenyl-ϒ- amino-butyric acid)? Baclofen Phenibut is a primarily a GABA-B receptor agonist. It is prescribed in Russia as an anxiolytic and can be purchased online as…
June Message from AACT President, Dr. Kirk Cumpston
June 30, 2021 June is a great month for so many reasons. The crescendo of high school and undergraduate finals punctuates months of educational labor, creating a pleasant slide into the freedom of summer. The graduating residents and fellows are moving on to their future…
Question of the Day – Wednesday June 30, 2021
What antipsychotic is known to produce sialorrhea despite its antimuscarinic effects? Clozapine. Clozapine antagonizes muscarinic receptors, producing antimuscarinic effects in overdose. However, it paradoxically acts as an agonist at the M4 subtype receptor and produces sialorrhea. Praharaj, Samir Kumar, Arora, Manu, & Gandotra, Sachin. (2006)….
Question of the Day – Tuesday June 29, 2021
Consumption of which animal can lead to the development of acute rhabdomyolysis? European migratory quails (Coturnism). Acute rhabdomyolysis develops when damage to striated muscles occurs. A rarely reported cause of this syndrome is quail poisoning, also known as coturnism. Coturnism may develop after consumption of…
Question of the Day – Monday June 28, 2021
Name the plant. Podophyllum peltatum Personal image credit to Dr. Michael Hodgman. Verified by PictureThis™