Question -What dose of naloxone should be considered in the acute treatment of pediatric patients suffering an overdose of the drug clonidine?
Answer- A recently published retrospective descriptive cohort study of hospital medical records for pediatric patients concluded “Administration of high-dose naloxone (10 mg) should be considered in all children with clonidine toxicity.” (Seger DL and Loden JK. Naloxone reversal of clonidine toxicity: dose, dose, dose. 2018 Clin Tox 56(10:873-879)
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