This substance was added to the World Doping Agency (WADA) list of banned substances in 2016. It inhibits the carnitine transport type 2 and reduces l-carnitine biosynthesis. It may improve energy metabolism during hypoxia.
Meldonium inhibits the carnitine transporter type 2 and is now considered a banned substance by WADA. Marina Sharapova tested positive for this substance and was suspended for 15 months. (Greeblatt HK et al. Meldonium: A Performance Enhancing Drug? Clinical Pharmacology in Drug Development 2016; 5(3): 167-169.)