Question - What is the only drug currently approved by the FDA to treat benzodiazepine-refractory status epilepticus?
Answer- The cited article notes “Of the three medications most commonly used to treat benzodiazepine-refractory status epilepticus — levetiracetam, fosphenytoin, and valproate—only fosphenytoin is labeled by the Food and Drug Administration (FDA) for this indication in adults, and none has been approved for children. (Kapur J et al. Randomized trial of three anticonvulsant medications for stats epilepticus. 2019 NEJM 381:2103-2113.)