Question - What is the basis for nickel allergy that might be associated with the treatment of cerebral aneurysms?
Answer - The cited article notes “Nickel is a major component of the cobalt alloy used in aneurysm clips and also of nitinol, which is commonly used in flow diverters and intra- cranial stents.” (Tsang A. et al. Nickel related adverse reactions in the treatment of cerebral aneurysms: A literature review. 2018 World Neurosurg. 115:147-153)