What is the proposed mechanism by which red ginseng prevents doxorubicin-induced cardiomyopathy?
In an animal model, Yoshikawa N et al. found that red ginseng increased antioxidant activity and inhibited cell death via activation of Nrf2 pathway.
Yoshikawa N, Hirata N, Kurone Y, Shimoeda S. Red ginseng prevents doxorubicin-induced cardiomyopathy by inhibiting cell death via activating the Nrf2 pathway. Cardiooncology. 2024 Jun 22;10(1):39. doi: 10.1186/s40959-024-00242-0.
Contributed by Kristin Reinaker, PharmD, DABAT on behalf of Rachel Lee, PharmD candidate 2025
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