According to a recent study, what characteristics are associated with diphenhydramine toxicity that result is more severe outcomes?
Acidemia, prolonged QRS and elevated anion gap.
Hughes AR, Lin A, Hendrickson RG; Toxicology Investigator’s Consortium (ToxIC). Clinical and patient characteristics associated with severe outcome in diphenhydramine toxicity. Clin Toxicol (Phila). 2021 Oct;59(10):918-925. doi: 10.1080/15563650.2021.1891244. Epub 2021 Mar 5. PMID: 33666139.
Submitted by: Molly Stott, PharmD and Dawn Sollee, PharmD, DABAT on behalf of Florida/USVI Poison Information Center – Jacksonville
Posted in Question Of The Day