This drug recently was shown to cause a mean weight loss of 14.9% from baseline over a 68 week time period.
Semaglutide 2.4 mg once weekly resulted in a mean weight loss of 14.9% from baseline with lifestyle interventions in a recent study over a 68 week time frame.
Wilding JPH et al. Once-Weekly Semaglutide in Adults with Overweight or Obestiy. NEJM Feb 10 2021; DOI: 10.1056/NEJMoa2032183