In 1981, in Spain, the ingestion of an oil fraudulently sold as olive oil caused an outbreak of a previously unrecorded condition, later known as toxic oil syndrome (TOS). Among survivors, there is a high prevalence what chronic conditions?
Scleroderma (9-13%) and neuromuscular changes. Neuromuscular changes included contractures and obvious motor neuropathy (around 10%), cramps (70-80%), and paresthesias (60-70%).
Gelpí E, de la Paz MP, Terracini B, et al. The Spanish toxic oil syndrome 20 years after its onset: a multidisciplinary review of scientific knowledge. Environ Health Perspect. 2002;110(5):457-464. doi:10.1289/ehp.110-1240833