These side effects have been reported after linezolid particularly with treatment for greater than 28 days?
Myelosuppression, lactic acidosis and optic and peripheral neuropathy have all been reported secondary to linezolid particularly with long term treatment. (Palenzuela L et al. Does Linezolid Cause Lactic Acidosis by Inhbiting Mitochrondial Protein Synthesis? Clinical Infectious Diseases 2005; 40:e113-116; Lee E et al. Linezolid-associated toxic optic neuropathy: a report of 2 cases. Clin Infect Dis 2003; 37:1389-1391; Bressler AM et al.Peripheral neuropathy associated with prolonged use of linezolid. Lancet Infec Dis 2004; 4:528-531.)