According to an article by Koivusalo, et al, in toxic paracetamol ingestions what benefit is there in the use of MARS therapy in addition to NAC?
Improvement in liver function which can allow hepatic recovery or allow time for bridging to transplantation.
Koivusalo AM, Yildirim Y, Vakkuri A, Lindgren L, Höckerstedt K, Isoniemi H. Experience with albumin dialysis in five patients with severe overdoses of paracetamol. Acta Anaesthesiol Scand. 2003 Oct;47(9):1145-50. doi: 10.1034/j.1399-6576.2003.00190.x. PMID: 12969110.
Contributed by Bailey Peacock, MD PGY-2 Emergency Medicine Residency, UF Health Jacksonville, on behalf of the Florida Poison Information Center Network
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