What is the major metabolite of aniline?
4 healthy male volunteers were given 5 mg isotope-labeled aniline to evaluate the metabolism and excretion kinetics. N-acetyl-4-aminophenol was the predominant urinary aniline metabolite.
Modick H et al. Human metabolism and excretion kinetics of aniline after a single oral dose. Arch Toxicol 2016 Jun;90(6):1325-33. doi: 10.1007/s00204-015-1566-x. Epub 2015 Aug 2.
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