Question-The orellanus syndrome is associated with the ingestion of orellanine found in the Cortinarius specie of mushroom. What are the clinical characteristics of this syndrome?
Answer- The cited article reports “Orellanus syndrome usually starts with a latent phase (which can vary from 12 hours to 14 days, with a median of 3 days), followed by a pre-renal phase, with systemic and gastrointestinal symptoms (nausea, vomiting, and diarrhea), and an oliguric renal phase. The renal phase of the poisoning can appear while the gastrointestinal symptoms are still present, usually after a period of 3 days up to 17 days. Out of 70% of the cases, renal damage progresses toward chronic renal failure, which justifies renal replacement therapy in 10-50% of the cases.” (Esposito P et al. Renal; involvement in mushroom poisoning: The case of orellanus syndrome. 2015 Hemodialysis International 19: E1-E5)