Historical QOD 11/21/08: In the early 1980’s a number of young adults in northern California developed a dense parkinsonian syndrome following the IV use of what was thought by them to be synthetic heroin. Subsequent investigation determined this material to contain what chemical that has also been used to develop an animal model for Parkinson’s Disease?
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).n
Fukuda T. Neurotoxicity of MPTP. Neuropathology. 2001 Dec;21(4):323-32. doi: 10.1046/j.1440-1789.2001.00402.x. PMID: 11837540.
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