What is the proposed mechanism of ifosfamide encephalopathy?
The exact mechanism is not fully elucidated however it is believed that one of the metabolites, chloracetaledehyde, is the causative agent of ifosfamide induced encephalopathy.
David KA. Evaluating Risk factors for the Development of Ifosfamide Encephalopathy. Am J Clin Oncol 2005; 28: 277-280
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