Question - Domoic acid is an excitatory amino acid that can accumulate in certain shell and fin fish. Domoic acid is structurally similar to the neurotoxin kainic acid. Domoic acid and kainic acid are analogs to what important neurotransmitter?
Answer - The cited article notes “Both domoic acid and kainic acid are analogs of an important neurotransmitter, the excitatory amino acid glutamate, and indeed both mimic glutamate in its interaction with some of its receptor subtypes.” (Costa LG et al. Domoic acid as a developmental neurotoxin. 2010 Neurotoxicology 31:409-423)