Question - Sofosbuvir-based regimens have been highly successful in the treatment of patients with chronic hepatitis C virus infection. What potentially serious arrhythmias have been reported in association with the use of sofosbuvir-based regimens?
Answer- Symptomatic bradyarrhythmias have been reported in association with the use of sofosbuvir-based regimens. (Fontaine H et al. Bradyarrhythmias associated with sofosbuvir treatment. 2015 NEJM 373:1886-1888)
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