In a recent Israeli outbreak of brodifacoum exposure from synthetic cannabinoid use, what was the most common presenting symptom?
According to the cited reference: “The most common presenting symptom was urinary tract bleeding (53%), followed by gastrointestinal bleeding (50%), and 43 patients (60%) had multiple bleeding sites. The most severe complications were intracranial bleeding in three patients (4%) and hemothorax in two patients (3%), one of whom had combined hemothorax/pericardial bleeding.”
Lurie Y, Nadir Y, Hoffman R, Miller A, Efrati E, Ring G, Sonenfeld D, Bar N, Zaidani H, Strizevsky A, Asali M, Lavon O, Kurnik D. An outbreak of severe coagulopathy in northern Israel among users of illicit synthetic cannabinoids adulterated with brodifacoum. Clin Toxicol (Phila). 2023 Jun;61(6):429-435. doi: 10.1080/15563650.2023.2215402. Epub 2023 Jun 9. PMID: 37293741.