What is the utility of dialysis in the setting of intentional ingestion of Yew leaves?
Due to its pharmacokinetic characteristics of high volume of distribution, molecular weight, and protein binding, Taxine B is not effectively removed by hemodialysis.
Buetler VA, Braunshausen AM, Weiler S, Klukowska-Rötzler J, Exadaktylos AK, Liakoni E. Characteristics of emergency department presentations following ingestion of Taxus baccata (yew). Clin Toxicol (Phila). 2023 Jan 3:1-6. doi: 10.1080/15563650.2022.2158097. Epub ahead of print. PMID: 36594830.
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