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May 24, 2019

Question of the Day – Friday May 24, 2019

Question - The cited reference states “Clinically significant scorpion envenomation by Centruroides sculpturatus produces a dramatic neuromotor syndrome and respiratory insufficiency that often necessitate intensive supportive care.” What is the clinical syndrome associated with scorpion envenomation by Centroides sculpturatus?

Answer- The cited article reports “The clinical syndrome includes uncoordinated neuromotor hyperactivity, oculomotor and visual abnormalities, and respiratory compromise due to abundant respiratory secretions, airway obstruction, aberrant ventilatory effort, and occasional noncardiogenic pulmonary edema.The clinical pattern is a consequence of specific ion-channel toxins in the scorpion venom, which stimulate or potentiate action potentials throughout the peripheral nervous system.” (Boyer LV et al. Antivenom for critically ill children with neurotoxicity from scorpion stings. 2009 NEJM 360:2090-2098)

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  • Education & Groups
    • American Board of Applied Toxicology (ABAT)
      • ABAT Exceptional Service Award
      • ABAT Newsletter
      • Sitting for the American Board of Applied Toxicology Exam
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      • ABAT Member Directory
        • Diplomate Verification
      • ABAT Board of Directors Contact Information
    • E-Learning
      • Research Seminar: The Nuts and Bolts of Toxicology Research
      • Advanced Hazmat Life Support Training
      • MMTI Fundamentals for Front-Line Practitioners Training
      • TOXISMO Society for the Discussion of Scientific Literature
      • ToxNow
      • Webinars
        • ABAT Journal Club Webinars
        • COVID Webinar Series
    • Toxicology Residency & Fellowship Training Programs
    • Clinical Toxicology Guidelines Collaborative
      • Recommendations
    • Fellows of AACT
    • ToxCoach Mentorship Program
    • Committees
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      • Acute & Intensive Care
      • Addiction Toxicology Section
      • Clinical Toxicology In Sports
      • Diversity, Equity, and Inclusion Section
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