Question - The cited reference states “Clinically significant scorpion envenomation by Centruroides sculpturatus produces a dramatic neuromotor syndrome and respiratory insufficiency that often necessitate intensive supportive care.” What is the clinical syndrome associated with scorpion envenomation by Centroides sculpturatus?
Answer- The cited article reports “The clinical syndrome includes uncoordinated neuromotor hyperactivity, oculomotor and visual abnormalities, and respiratory compromise due to abundant respiratory secretions, airway obstruction, aberrant ventilatory effort, and occasional noncardiogenic pulmonary edema.The clinical pattern is a consequence of specific ion-channel toxins in the scorpion venom, which stimulate or potentiate action potentials throughout the peripheral nervous system.” (Boyer LV et al. Antivenom for critically ill children with neurotoxicity from scorpion stings. 2009 NEJM 360:2090-2098)