What strategies can be employed to manage side effects of buprenorphine/naloxone?
According to the cited reference, there are several strategies to manage side effects of buprenorphine/naloxone: (1) gradual dose reduction while monitoring for withdrawal, (2) split dosing to minimize side effects related to rapid increases in medication levels, (3) adjunctive medications to target side effects, (4) transition to another buprenorphine/naloxone product or to a buprenorphine mono product, (5) continue treatment as is as some side effects diminish over time.
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