Question - What hepatic complication, characterized by pruritus and jaundice accompanied by moderate-to-marked elevations in alkaline phosphatase levels is noted to be caused by amoxicillin–clavulanate, cephalosporins, terbinafine, azathioprine, and temozolomide.
Answer - Cholestatic hepatitis is noted to be caused by amoxicillin–clavulanate, cephalosporins, terbinafine, azathioprine, and temozolomide. (Hoofnagle JH and Bjornsson ES. Drug induced liver injury- Types and phenotypes.2019 NEJM 381:264-273)
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