In a rat model, what treatment was shown to reduce neuropathic pain from paclitaxel?
Melatonin. McCormick et al. administered various doses of melatonin to rats given paclitaxel. Melatonin 10 mg/kg/day was the most effective.
McCormick B et al. Melatonin as a potential treatment for paclitaxel induced peripheral neuropathic pain. British Journal of Anaesthesia; 2017; 199(2): e1-e20. https://doi.org/10.1093/bja/aew382
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