Question of the Day – Tuesday August 14, 2018

Question – What biomarkers may be useful in determining occupational exposure to asphalt fumes?

Answer – The cited reference notes “Urinary thioether excretion, glucaric acid metabolites in urine, detection of mutagens in urine, sister chromatid exchange and primary DNA damage in lymphocytes, urinary 1-hydroxypyrene, and DNA or protein adducts have been described as indicators of exposure to or effects of asphalt fumes.” (“Heath Effects of Occupational Exposure to Asphalt” available at: https://www.cdc.gov/niosh/docs/2001-110/pdfs/2001-110.pdf?id=10.26616/NIOSHPUB2001110; accessed July 2018)