Question- What is the bioavailability of oral cannabidiol and how long does the drug take to reach peak blood concentrations?
Answer-The cited reference notes “oral cannabidiol bioavailability varies ranging between 13 and 19%, and the drug can take up to 3 hours to reach peak concentrations.” (Donvito G., et al. The endogenous cannabinoid system: a budding source of targets for treating inflammatory and neuropathic pain. 2018 Neuropsychopharm. 43:52-79 as cited in Ross E. Discourage the use of medical marijuana. 2018 NEJM 379(16):1576-1577).
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