Question of the Day – Friday August 17, 2018

Question – Drug induced aseptic meningitis has been reported to be associated with a number of different medication classes including antibiotics, anti inflammatory drugs and immunomodulators. What antibiotic is the most common cause for antibiotic related aseptic meningitis?

Answer – Trimethoprim sulfamethoxazole is the antibiotic that is most commonly implicated as causing aseptic meningitis. (Bruner KE et al. Trimethoprim-sulfamethoxazole-induced aseptic meningitis-not just another sulfa allergy. 2014 Ann Allergy Asthma Immunol 113: 520-526)