Question of the Day – Tuesday July 25, 2017

Question: Which drug has been shown to rapidly and safely reverse the anticoagulant effect of dabigatran (Pradaxa)?

Answer:  Idarucizumab (Praxbind) has been shown to rapidly and safely reverse the anticoagulant effect of dabigatran in patients with uncontrolled bleeding or those taking dabigatran and who need to undergo an urgent or emergent procedure. (Pollack CV et al. Idarucizumab for dabigatran reversal. 2015 NEJM 373(6): 511-520)