Question: Fentanyl administered by intravenous bolus can be associated with cough that may, at times, be severe. What are the risk factors for the development of fentanyl-induced cough?
Answer: One study reports “………..significant independent risk factors for the development of fentanyl-induced cough include, a young age and absence of cigarette smoking, the absence of epidurally administered lidocaine and the absence of a priming dose of vecuronium.” (Oshima T et. al. Identification of independent risk factors for fentanyl-induced cough. 2006 Can J Anesth 53(8):753-758)