Question: Based on the presumed cardiovascular fluctuations affecting the uteroplacental unit in pregnant cocaine users what are the overall risks of labor-related adverse events in this population?
Answer: According to the cited reference, based on the presumed cardiovascular fluctuations affecting the uteroplacental unit in pregnant cocaine users “the overall risks of labor-related adverse events in this population are increased as follows: preterm labor 17.4%, precipitous labor 13.4%, placental abruption 17.3%, abnormal fetal monitoring 15.3%, and meconium-stained fluid 25%” (Chasnoff IJ, et al. Cocaine use in pregnancy: perinatal morbidity and mortality. Neurotoxicol Teratol. 1987, 9:291–293 as cited in cain MA et al. The Maternal, fetal, and neonatal effects of cocaine exposure in pregnancy. 2013 Clin Obstet Gyn, 56 (1): 124-132)