Question: What are the reported central nervous system manifestations associated with neonatal abstinence syndrome?
Answer: The reported central nervous system manifestations associated with neonatal abstinence syndrome include tremors, high pitched crying, sleep disturbances, increased muscle tone, excoriations, irritability, and seizures. (McQueen K et al. Neonatal abstinence syndrome. 2016 NEJM 375(25): 2468-2479)
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