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 Lampe-Kunkle Memorial Award
 for Research on Natural Products of Toxicology
 Deadline for submission of proposals is June 1

The American Academy of Clinical Toxicology (AACT) announces a call for submission of protocols for the Lampe-Kunkle Memorial Award. Up to $1,500 is available to fund one study. An additional award of a maximum of $750 will be provided for travel to the NACCT to present the results of the project. The goal of this grant program is to provide competitive funding for original research, utilizing standard experimental design to investigate some aspect of toxicity due to naturally occurring phenomenon (i.e., plants, mushrooms, algae, insects, snakes). The intended research should advance the mission of the AACT to unite “scientists and clinicians in the advancement of research, education, prevention and treatment of diseases caused by chemicals, drugs and toxins.” The project may be part of a larger project but must have a specific hypothesis, aims and obtainable results that are separate and distinct. Completed applications must be received by June 1. Questions about the process should be directed to the AACT administrative office at 717-558-7847 or swilson@pamedsoc.org.

Directions for Submission of Proposals
Include blinded copies of information where indicated. This means that information should be on plain white paper with no identifying marks. (e.g., letterhead, institution name, applicant name, etc.)

Eligibility
The primary investigator must be a member in good standing of AACT. Applicants may not be members of the AACT Research Committee.

Funding
Up to $1,500 is available to fund one study. An additional award of a maximum of $750 will be provided for travel to the NACCT the following year to present the results of the project.

Funding can be used for costs associated with subject recruitment, laboratory analysis, data management, statistical analysis, and other similar activities. AACT will not fund requests for principal and/or site investigator salaries, institutional indirect costs, or capital equipment purchases.

All of the awarded funds will be disbursed at study initiation.

Applications

Cover Letter
Applications must include a cover letter that contains a statement that the protocol is being submitted as the investigator's intellectual property. The investigators must provide justification that their requested funding will allow them to complete the protocol as submitted. The investigator must state whether or not the protocol is currently being considered for funding by any other organization. If the protocol is concurrently funded, or being considered for funding by any other organization, the investigator must state that they will not accept duplicate funding. A statement that the investigator will provide copies of all institutional review board approvals prior to disbursement of funds must also be included. The investigator must also state that they agree that Clinical Toxicology, the official journal of the AACT, has the right of first refusal of all manuscripts resulting from the funded project. The investigator should also state that they will submit an abstract of the results of this project to the North American Congress of Clinical Toxicology (NACCT) in the year following completion of the research and that they expect to be able to attend the NACCT to receive the research award. The investigator must also state that all presentations and publications of the research will recognize the AACT as the source of study funding.

Protocol

The protocol should be limited to no more than 6 pages, single-spaced with one-inch margins, excluding a one-page coversheet. The protocol should be blinded as described previously. The following should be included within the protocol:


  1. An introduction that clearly demonstrates the importance of the proposed study, its potential impact on clinical toxicology, and a discussion of relevant prior work. The introduction should clearly state the expected benefits of the proposed research;

  2. A clear statement of the scientific hypothesis that will be tested and primary and secondary trial outcomes;

  3. Sample size and power calculations;

  4. A discussion of the informed consent process that will be utilized;

  5. Detailed study methods;

  6. Study timeline; and

  7. A description of the feasibility of successful completion of the proposed study. (This should include support for estimates of expected patient enrollment rates, availability of resources needed to complete the protocol, and any other evidence that supports the investigators' ability to successfully complete the study protocol in the time period described.)

Supporting Documents
The following supporting documents should also be included:

  1. Letters of participation/agreement from each site investigator;

  2. Curricula vitae for all investigators;

  3. A detailed budget that includes all in-kind or matching support from the investigator's institution or other sources must be provided. A justification for each component of the budget must also be included; and

  4. Documentation from the host institution's Grants Management Office indicating the waiver of all indirect costs.

Eight (8) copies of the cover letter, application, and any supporting documents must be received by the AACT administrative offices by June 1.

AACT Executive Office
777 E. Park Drive, PO Box 8820
Harrisburg, PA 17105-8820

Criteria for Evaluation of Research Award Applications
Review will be blinded as to author and institution. Authors should avoid using any identifying references within the body of the paper. The Research Awards Committee will be asked to evaluate proposals based upon the following criteria:

  • Clear statement of objectives/hypothesis to be tested.
  • Logical statement of the rationale why this project needs to be completed.
  • Summary of related work in the area.
  • Understandable discussion of the methodology to be employed.
  • Description of the statistical analysis as appropriate.
  • Clear statement of the significance of the proposed project to the field of clinical toxicology.
  • Feasibility of the project within the time and budget limitations.


Progress Reports
A progress report should be submitted six months after disbursement of the award and at completion of the study. A copy of the article that emanates from this research should also be submitted upon publication.